| CTRLSHIFTV–Paste text into the address bar and go | Navigation |
| ALTENTER–Open the typed address in a new tab | Navigation |
| F5–Reload the page | Navigation |
| CTRLR–Reload the page | Navigation |
| CTRLF5–Reload the page without caching | Navigation |
| HOME–Go to the top of the page | Navigation |
| END–Go to the bottom of the page | Navigation |
| PAGE DOWN–Go up one screen height | Navigation |
| PAGE UP–Go down one screen height | Navigation |
| CTRLBACKSPACE–Go to the home page | Navigation |
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| ALT←–Go to the previous page | Navigation |
| ALT→–Go to next page | Navigation |
| ALTHOME–Go to Speed Dial | Navigation |
| CTRLSHIFTW–Close window | Windows |
| CTRLN–New window | Windows |
| CTRLSHIFTN–Open incognito window | Windows |
| CTRLSHIFTT–Restore closed tab | Tabs |
| CTRLW–Close tab | Tabs |
| CTRLF4–Close tab | Tabs |
| CTRLM–Open tab menu | Tabs |
| CTRLTAB–Go to next tab | Tabs |
| CTRLSHIFTTAB–Go to previous tab | Tabs |
| CTRLPAGE UP–Go to the previous tab | Tabs |
| CTRLPAGE DOWN–Go to the next tab | Tabs |
| CTRL1..9–Go to the tab by its ordinal number | Tabs |
| CTRLT–Open a new tab | Tabs |
| CTRLSHIFTB–Open Bookmark Manager | Bookmarks |
| CTRLD–Add page to bookmarks or express panel | Bookmarks |
| CTRLF–Find on page | Search |
| F3–Find next | Search |
| SHIFTF3–Find previous | Search |
| CTRLG–Find next | Search |
| CTRLSHIFTG–Find Previous | Search |
| CTRLH–History | History |
| CTRLSHIFTDELETE–Delete Recent History | History |
| CTRLJ–Downloads | Tools |
| CTRLSHIFTE–Extensions | Tools |
| CTRLSHIFTS–Side Menu On/Off | Page View |
| ALT–Open Main Menu (When Released) | Page View |
| ALTF–Open Main Menu | Page View |
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| CTRL0–Zoom 100% | Page View |
| F11–Full Screen Mode On/Off | Page View |
| CTRL+–Zoom Page | Page View |
| CTRL-–Zoom Out | Page View |
| CTRL←–Move Cursor to Previous Word | Text |
| CTRL→–Move Cursor to Next Word | Text |
| CTRLL–Move Cursor to Address Bar | Text |
| CTRLY–Redo Last Undo | Text |
| CTRLBACKSPACE–Delete Word Before Cursor | Text |
| CTRLDELETE–Delete Word After Cursor | Text |
| CTRLSHIFTX–Exit Opera | File |
| CTRLO–Open File | File |
| CTRLP–Print Document | File |
| CTRLSHIFTP–Print document (without preview) | File |
| CTRLS–Save page as | File |
| ←–Previous page | PDF document |
| →–Next page | PDF document |
| CTRLU–Open page source in a new tab | Development |
| CTRLSHIFTC–Open page source in Developer Tools | Development |
| CTRLSHIFTI–Show / Hide Developer Tools console | Development |
| CTRLSHIFTJ–Open / Hide Developer Tools console | Development |
| ALTP–Open settings | Other |
| CTRLF12–Open settings | Other |
| SHIFTESC–Show Opera Task Manager | Other |