| CTRLM–Minimize Telegram | General |
| CTRLW–Minimize Telegram to the taskbar | General |
| CTRLL–Lock Telegram (if a lock password is set) | General |
| CTRLQ–Close the app completely | General |
| ALT↑–Go to the previous chat | Navigation |
| ALT↓–Go to the next chat | Navigation |
| CTRLF–Search the selected chat | Navigation |
| CTRL0–Go to Favorites (saved messages) | Navigation |
| CTRL1..5–Switch between pinned chats | Navigation |
| CTRLO–Open the window for selecting files to send to Telegram | Messages |
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| CTRLUp–Select messages for quick reply | Messages |
| Up–Edit last message | Messages |
| DELETE–Delete selected messages | Messages |
| CTRLB–Make bold | Formatting |
| CTRLI–Make italic | Formatting |
| CTRLU–Underline | Formatting |
| CTRLSHIFTX–Strikethrough | Formatting |
| CTRLSHIFTM–Monospace font (code) | Formatting |
| CTRLK–Create hyperlink | Formatting |
| CTRLSHIFTN–Undo formatting | Formatting |